At-home dosing and administration

The NUCALA Autoinjector for at-home administration.

Easy to use

At-home convenience

  • Study Description

    12-week, open-label study assessed the correct use of the NUCALA Autoinjector in patients aged ≥12 years with severe eosinophilic asthma (n=104). NUCALA was administered as one 100-mg subcutaneous injection every 4 weeks by the patient or caregiver after being trained on proper technique with the Autoinjector at baseline. Successful use was determined by investigator observation using a checklist of steps based on Instructions for Use and visually inspecting the Autoinjector following the third dose. Ease of use and convenience of use at home were measured at study end on a 5-point scale (not at all, a little, moderately, very, and extremely) in the 102 patients with successful use.1,2

NUCALA offers:

  • Once-monthly dosing (every 4 weeks)
  • No loading dose
  • Fixed-dose (independent of weight)

At-home dosing and administration with the NUCALA Autoinjector:

  • Fixed 100-mg dose independent of weight
  • NUCALA may be administered by the patient or a caregiver
  • Subcutaneous injection every 4 weeks into the thigh or abdomen (or upper arm by caregiver)
  • Intended for use under HCP guidance. Provide proper training on injection technique and administration using the Instructions for Use after determining at home use is appropriate.

Administration of NUCALA with a single-use Autoinjector or 100 mg/mL prefilled syringe

How to use the Autoinjector

How to use the 100 mg/mL prefilled syringe

Keep NUCALA and all medicines away from children.


  • Do not use any Autoinjector or prefilled syringe more than 1 time.
  • Do not share the Autoinjector or prefilled syringe with other people.
  • Do not use the Autoinjector or prefilled syringe if it was dropped or looks damaged.


  • Store in the refrigerator between 36°F to 46°F (2°C to 8°C)
  • Keep in the original carton until time of use to protect from light
  • Do not freeze
  • Do not shake
  • Keep away from heat
  • If necessary, an unopened carton can be stored outside the refrigerator at up to 86°F (30°C) for up to 7 days
  • Do not use the Autoinjector or prefilled syringe if it has been left out of the carton for more than 8 hours



Autoinjector: A physician perspective

Autoinjector: A patient perspective