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How to use the NUCALA Autoinjector at home

In this video, your appropriate patients can learn how to administer NUCALA at home using the NUCALA Autoinjector when their prescribed dose requires multiple injections.

  • transcript

    TEXT ONSCREEN:
    How to Use Your Prefilled Autoinjectors When Your Prescribed Dose Requires Multiple Injections

    Please see the full Instructions for Use at NUCALA.com.

    WOMAN:
    Hi. Today I’m going to help show you how to prepare for and take your NUCALA injection. First, your doctor should teach you how to use the Autoinjector. You should also read the full Instructions for Use in your NUCALA carton or at NUCALA.com.

    I’ll walk you through the injection like your doctor may have. If you have questions or concerns, you can always talk to your doctor about NUCALA. And remember: You got this. It shouldn’t take long for you to get more comfortable with injecting medicine yourself. Let’s get started.

    TEXT ONSCREEN:
    If you’ve been prescribed a 300 mg dose, make sure you take out and prepare three Autoinjector cartons.

    WOMAN:
    First, take the carton out of the refrigerator. Check to make sure the security seals aren’t broken. If a seal is broken, don’t use the Autoinjector and safely throw the carton away.

    Now, take the tray out of the carton. Peel off the clear plastic cover and, while holding the middle of the Autoinjector, carefully take it out. Before we begin, let’s look at the components of the Autoinjector.

    TEXT ONSCREEN:
    Do not     remove the clear needle cap at this step.
    [labels naming components of the Autoinjector]
    Clear needle cap
    Yellow needle guard     (needle inside)
    Stopper
    Label
    Inspection window     (medicine inside)

    WOMAN:
    Don’t remove the clear needle cap at this step.

    Check the expiration date on the label of your Autoinjector and make sure it hasn’t passed.

    TEXT ONSCREEN:
    Look at the medicine in the inspection window. It should be clear to pale yellow to pale brown in color and without cloudiness or particles.

    WOMAN:
    Look at the medicine in the inspection window. It’s normal to see one or more air bubbles. It should be clear to pale yellow to pale brown in color. If it’s cloudy, discolored, or has particles floating in it, don’t use it.

    Now put the Autoinjector down on a clean, flat surface at room temperature, away from direct sunlight and out of the reach of children. Don’t try to warm it up any other way.

    TEXT ONSCREEN:
    Wait 30 minutes.

    WOMAN:
    You’ll need to wait 30 minutes before use.

    TEXT ONSCREEN:
    Do not     use if left out more than 8 hours.

    WOMAN:
    Don’t use it if it’s left out of the carton more than 8 hours.

    TEXT ONSCREEN:
    Supplies you need

    • Alcohol swab
    • Cotton ball or gauze
    • Adhesive bandage
    • Sharps disposal container

    WOMAN:
    You can take this time to gather the supplies you need: an alcohol swab; a cotton ball or gauze; an adhesive bandage; and a sharps disposal container. The Autoinjector is only for use under the skin.

    TEXT ONSCREEN:
    The Autoinjector is only for use under the skin (subcutaneous).

    TEXT ONSCREEN:
    You can inject in your thigh or abdomen.

    • Do not inject where your skin is bruised, tender, red, or hard.
    • Do not inject within 2 inches of your belly button.

    WOMAN:
    Now you can choose your injection site. You can inject yourself in your thigh or abdomen.

    TEXT ONSCREEN:
    Your caregiver or healthcare provider can also inject in the upper arm.

    WOMAN:
    Or if you’re a caregiver or healthcare provider giving the injection to someone else, you can also choose to inject in the upper arm.

    TEXT ONSCREEN:
    If you need more than one injection to complete your dose, leave at least 2 inches between each injection site.

    WOMAN:
    If you need more than one injection to complete your dose, leave at least 2 inches between each injection site.

    TEXT ONSCREEN:
    After cleaning the injection site, don’t touch the area again until after the injection.

    WOMAN:
    Now, wash your hands well with soap and water. Clean the area you want to inject by wiping your skin with an alcohol swab and allowing it to air-dry.

    Now remove the clear needle cap from the Autoinjector by pulling it straight off. This could take a little force. You may see a drop of medicine at the end of the needle, and that’s normal.

    TEXT ONSCREEN:
    Inject within 5 minutes after you remove the clear needle cap.

    WOMAN:
    Always inject within 5 minutes after you remove the clear needle cap. Do not touch the yellow needle guard with your fingers, and don’t put the needle cap back onto the Autoinjector, because that could accidentally start the injection.

    Touching the yellow needle guard may also cause a needle injury.

    Hold the Autoinjector so you can see its inspection window. Place the Autoinjector straight onto your injection site with the yellow needle guard flat on the surface of your skin.

    TEXT ONSCREEN:

    • Push & Hold
    • 1st Click
    • 2nd Click
    • Count to 5
    • Lift

    WOMAN:
    To start your injection, push the whole Autoinjector all the way down and keep it held down against your skin. This will make the yellow needle guard slide up into the Autoinjector. If the yellow needle guard does not slide up, don’t use the Autoinjector; throw it away in a sharps disposal container.

    You should hear a click to let you know your injection has started. The yellow indicator will move down through the inspection window as you receive your dose. Don’t change the position of the Autoinjector, and hold it in place. Your injection may take up to 15 seconds to complete.

    Continue to hold until you hear the second click, the stopper has stopped moving, and the inspection window is filled with the yellow indicator. If you don’t hear the second click, check that the inspection window is filled with the yellow indicator, or hold the Autoinjector down for 15 seconds to make sure the injection is complete.

    After you hear the second click, continue to hold and count to 5.

    Then gently lift the Autoinjector away from your skin.

    TEXT ONSCREEN:
    Do not     put the needle cap back on.
    Do not rub your injection site.

    WOMAN:
    Do not put the needle cap back on. Don’t rub your injection site. You may see a small drop of blood, which is normal. Just press a cotton ball or gauze on the area and apply an adhesive bandage if you need it.

    TEXT ONSCREEN:

    • Dispose of the used Autoinjector and needle cap in an FDA-cleared sharps disposal container right
      away.
    • Do not throw away your used sharps disposal container in your household trash  unless your
      community guidelines permit this.
    • For more information about safe sharps disposal, visit www.fda.gov/safesharpsdisposal
    • Once you’ve safety discarded the Autoinjector, complete any remaining injections as prescribed by
      your doctor following the same instructions. Be sure each injection is at least 2 inches apart.

    WOMAN:
    To clean up, put your used Autoinjector in a sharps disposal container right away, and keep the container out of the reach of children.

    That’s it for the injection! Once you do a few of these, it should become just another part of your treatment routine.

    TEXT ONSCREEN:
    844-4-NUCALA
    Monday – Friday, 8 AM – 8 PM ET

    Nurses from MyNUCALA.com don’t give medical advice.  Talk to your healthcare provider about any disease-, treatment-, or referral-related questions.

    WOMAN:
    If you have any questions or need more information, talk to your doctor. You can also call the Nurse Support Line at 844-4-NUCALA to get help with your injections or any general questions you have about NUCALA. For additional resources and support, you can turn to MyNUCALA. Look for it on NUCALA.com.

    TEXT ONSCREEN:
    Trademarks are owned by or licensed to the GSK group of companies. ©2020 GSK or licensor. MPLVID220027 November 2022. Produced in USA.

Intended for use under HCP guidance. Provide proper training on injection technique and administration using the full Instructions for Use after determining at-home use is appropriate.

STORAGE INFORMATION

  • Store in the refrigerator between 36˚F and 46˚F (2˚C and 8˚C).
  • Keep in the original carton until time of use to protect from light.
  • Do not freeze. Do not shake. Keep away from heat.
  • If necessary, an unopened carton can be stored outside the refrigerator at up to 86˚F (30˚C) for up to 7 days.
  • Safely throw away the Autoinjector if it is left out of the refrigerator for more than 7 days.
  • The Autoinjector must be used within 8 hours after you take it out of the carton. Safely throw it away if it is not used within 8 hours.
  • Safely throw away medicine that is out of date or no longer needed.

Keep NUCALA and all medicines out of the reach of children.

Warnings

Do not use the Autoinjector more than 1 time. Throw away the Autoinjector in an FDA-cleared sharps disposal container after your injection.
Do not share the Autoinjector with other people. You may give other people a serious infection, or you may get a serious infection from them.
Do not use the Autoinjector if it was dropped or looks damaged.

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